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Diseases of Development
Mathematical models for polio epidemics explanation and optimization of bladder cancer immunotherapy
Английски език
153 b
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Diseases of development are diseases associated §with industrial and social progress, whereby periods §of great human achievements paradoxically coincide §with negative manifestations in broad patterns of §health. In this book we investigate mathematical §models concerned with some of the better known §diseases of development. The first part of the book §is devoted to the study of poliomyelitis epidemics §in developed countries.In the second part of the §book, we consider a particular form of cancer, §bladder cancer, which is a widespread disease in the §developed word. The polio model is analysed in terms §of its bifurcation properties and in terms of its §nonequilibrium outbreak dynamics. We present the §first model for the treatment of bladder cancer via §immunotherapy with Bacillus Calmette-Gue rin (BCG). §The purpose of this research is to develop a §mathematical model described the tumor-immune §interactions in the bladder as a result of BCG §therapy.
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