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The Merriam-Webster's Collegiate Dictionary defined "melanoma" as a tumor that forms pigment characteristically; it was also one which was first described in 1838. Therefore, what has transpired between 1838 and 1900? In sum, Nordlund's associates did not answer that question with "THE EARLIEST STUDIES: PRE-1900. Accordingly, this book considers the pancreas which was missing in their account. The informative Merriam-Webster's Collegiate Dictionary not only defined melanoma as a tumor which forms pigment but also added that this name first appeared in 1838. In this context, a historical review of pigment cell biology did not mention the pancreas up to 1900. Therefore, this book briefly documents its appearances before that year.