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Contexte cellulaire et replication virale

Language FrenchFrench
Book Paperback
Book Contexte cellulaire et replication virale Sebastien Wurtzer
Libristo code: 07149397
Publishers Omniscriptum, February 2018
Pour illustrer l'importance du contexte cellulaire pour la réplication rétrovirale du VIH, deux pa... Full description
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67.70 €
132.42  лв
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Pour illustrer l'importance du contexte cellulaire pour la réplication rétrovirale du VIH, deux paramčtres ont été abordés: le premier concernait l'impact de modifications métaboliques des cellules cibles sur la résistance du VIH aux analogues de nucléosides; le second portait sur l'influence d'une structure particuličre du VIH sur la restriction rétrovirale par des protéines cellulaires. La transcription inverse du VIH peut ętre affectée par l'activation, la différenciation ou la division cellulaire. L'hypothčse que des changements dans le cycle cellulaire pourraient également affecter la susceptibilité du VIH-1 aux analogues de nucléosides a été émise. Par ailleurs, les lentivirus utilisent deux séquences riches en purines pour initier la synthčse d'un brin de l'ADN viral. Nous avons examiné en quoi l'initiation au niveau du PPT central pouvait protéger le génome viral de l'édition par des protéines APOBEC. Ces travaux démontrent en quoi l'environnement cellulaire peut influer sur la réplication du VIH et la sélection de variants résistants et élucident une nouvelle stratégie virale nécessaire ŕ la protection contre des facteurs antiviraux cellulaires.

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About the book

Full name Contexte cellulaire et replication virale
Author Sebastien Wurtzer
Language French
Binding Book - Paperback
Date of issue 2018
Number of pages 172
EAN 9786131546556
ISBN 613154655X
Libristo code 07149397
Publishers Omniscriptum
Weight 259
Dimensions 152 x 229 x 10

Categories

Biography, Literature & Literary studies > Literature: history & criticism > Literary studies: general
Mathematics & Science > Biology, life sciences > Microbiology (non-medical)
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