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This monograph provides an in-depth review of coronary circulation by international experts in the field. It focuses on recent major advances in basic research, but also includes discussion of clinical application, so that a multidisciplinary approach is achieved. The basic mechanisms of coronary circulation are covered, including the relationship between coronary flow and systolic and diastolic function, and the neural and humoral control of coronary tone. Other sections discuss coronary anatomy, blood flow dynamics, microcirculation, and regional myocardial flow.