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Peptide Arrays on Membrane Supports

Name: Peptide Arrays on Membrane Supports
Brand: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
SKU: 01563738
Price: 149.89 EUR
Availability: InStock
Author: Joachim Koch
ISBN: 9783540425328

Synthesis and Applications

Joachim Koch

Michael Mahler

Language

English

Book Paperback

Libristo code: 01563738

Publishers Springer-Verlag Berlin and Heidelberg GmbH & Co. KG, February 2002

Proteins interacting with diverse ligands - proteins, peptides or DNA - are the basic principles und... Full description

Libristo code: 01563738

365 b

149.89 €

293.15 лв

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Proteins interacting with diverse ligands - proteins, peptides or DNA - are the basic principles underlying many biological processes, such as antigen-antibody binding, signal transduction or receptor binding. The technique of oligopeptide synthesis on a cellulose membrane and the subsequent binding assays allow the investigation of protein interactions. A particular advantage of these peptide arrays (SPOT - technology) is the high number of oligopeptide probes that can be tested in parallel. Detailed protocols for peptide synthesis, and the analysis of protein-protein, protein-DNA interactions as well as epitope mapping are presented in this manual. It is ideally suited not only for basic research laboratories but also for diagnostic and therapeutic applications since many diseases are related to dysfunctions in protein recognition and binding.