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Polydnavirus Histone H4 and its role in insect immunity

Name: Polydnavirus Histone H4 and its role in insect immunity
Brand: LAP Lambert Academic Publishing
SKU: 06943390
Price: 172.95 EUR
Availability: InStock
Author: Wael Gad
ISBN: 9783659243981

Polydnavirus Histone H4

Wael Gad

Yonggyun Kim

Language

English

Book Paperback

Libristo code: 06943390

Publishers LAP Lambert Academic Publishing, November 2011

Cotesia plutellae (Braconidae: Hymenoptera) is a solitary endoparasitoid wasp that parasitizes the d... Full description

Libristo code: 06943390

421 b

172.95 €

338.26 лв

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Cotesia plutellae (Braconidae: Hymenoptera) is a solitary endoparasitoid wasp that parasitizes the diamondback moth, Plutella xylostella (L.) (Yponomeutidae: Lepidoptera). For successful parasitization, its symbiotic polydnavirus (CpBV) helps the wasps to attenuate host immune capacity and manipulate host developmental physiology. An analysis of CpBV genome sequence indicated the presence of one putative gene (CpBV-H4) showing a high similarity to histone H4. Histone H4, one of the four histone subunits along with H2A, H2B and H3, forms an eukaryotic nucleosome core. Along with H3, it plays a central role in nucleosome formation. CpBV-H4 showed expression in different tissues in parasitized P. xylostella. Transient expression of CpBV-H4 in nonparasitized P. xylostella resulted in significant impairment of hemocyte-spreading and decreased gene expression of host H4, while knock-down of the transient expression using double-stranded RNA interference recovered the immune capacity and gene expression.