Contact
How to shop
Delivery
Shopping guide
Protective Immunity against Hepatitis C
CORRELATES OF PROTECTIVE IMMUNITY IN INDIVIDUALS WHO ARE EXPOSED TO HEPATITIS C BUT APPEAR UNINFECTED
English
203 b
Up to 30 days for returns
Customers also purchased
/
Paperback
43.95
€
85.96 лв
/
Paperback
19.19
€
37.53 лв
/
Paperback
14.18
€
27.74 лв
/
Paperback
13.67
€
26.73 лв
A small subset of individuals who are exposed to HCV do not develop anti-HCV antibodies, persistent viraemia or chronic hepatitis despite generating HCV-specific CD4+ and CD8+ T cells. These individuals are believed to develop an immune response which rapidly clears viraemia prior to the induction of an antibody response. Cellular immune responses were evaluated in 23 infants born to HCV positive women. Responses were detected in 1/11 infants born to viraemic mothers, with cytokine production observed in an additional 3/5 infants. Responses were also assessed in multiply transfused subjects with thalassaemia. Responses were detected in 6/13 chronically infected subjects (46%), 4/7 subjects who had cleared infection (71%), and 14/17 seronegative subjects (82%). The third cohort were 41 seronegative injecting drug users, with responses detected in 6 (15%). HCV specific cellular immune responses in seronegative subjects were generally broad in specificity, with a generally Th-1 biased pattern of cytokine production. The findings suggest that responses can be maintained for decades after exposure, and may provide protection against repeated exposures.
About the book
English
Give this book today
It's easy
1 Add to cart and choose Deliver as present at the checkout 2 We'll send you a voucher 3 The book will arrive at the recipient's addressYou might also be interested in
/
Paperback
174.85
€
341.97 лв
/
Paperback
13.10
€
25.62 лв
/
Hardback
46.69
€
91.31 лв
Hi! I'm Libroamiko, your book advisor.
How can I help you?