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Thrombopathy and Bleeding manifestations in Patients with Dengue Fever

Name: Thrombopathy and Bleeding manifestations in Patients with Dengue Fever
Brand: LAP Lambert Academic Publishing
SKU: 12628513
Price: 33.92 EUR
Availability: InStock
Author: Bashir Abdrhman Bashir Mohammed
ISBN: 9783659882401

Thrombocyte Indices Evaluation

Bashir Abdrhman Bashir Mohammed

Language

English

Book Paperback

Libristo code: 12628513

Publishers LAP Lambert Academic Publishing, November 2015

Dengue fever (DF) and dengue hemorrhagic fever (DHF) are caused by the dengue virus. The main pathop... Full description

Libristo code: 12628513

82 b

33.92 €

66.35 лв

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Dengue fever (DF) and dengue hemorrhagic fever (DHF) are caused by the dengue virus. The main pathophysiological hallmark that distinguishes DHF from DF is the plasma leakage. Following this leakage, hypovolemic shock occurs as a consequence of a critical plasma volume loss. Constant hematological alterations occurring in DHF and frequently include bone marrow suppression, leukopenia and thrombocytopenia. An enhanced immune response of the host to a secondary Dengue Virus infection is a feature of DHF and leads to many consequences.The mechanisms underlying the bleeding in Dengue are multiple. These are vasculopathy, thrombopathy and disseminated intravascular coagulation (DIC). Thrombopathy consists of thrombocytopenia and platelet dysfunction. DIC is prominent in patients with dengue infection. The most severe DIC and massive bleeding are the result of prolonged shock and cause a fatal outcome. The mechanisms of thrombopathy and causes were discussed in this book.